The 2-Minute Rule for cees dekker
The 2-Minute Rule for cees dekker
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Employing solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic facets of the construction and dynamics of chromosomes. Our investigate pursuits consist of:
1996, very first mesoscopic demand density waves devices; and 1st electrical measurements on a single steel nanocluster involving nanoelectrodes
‘It was simply a matter of buying up a e book on cell biology and beginning to examine. I'd originate from a entire world of ultra-high vacuums, cryostats and quantum phenomena, and now I had been Doing work at space temperature with molecular biology kits.
Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2010, developed a fresh way (‘wedging transfer’) to control nanostructures; initially report of DNA translocation as a result of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into strong-state nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Quite a few similar developments adopted, where by our team founded different transistor variants such as single-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled numerous transistors into little proof-of-basic principle Digital circuits.
Example (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim in the pore is highlighted in pink, plus a 3D rendering of the motion of your DNA rod is shown.
The rotors harness Strength from ceesdekker a nanoscale h2o and ion circulation which is created by a static chemical or electrochemical probable gradient inside the nanopore, that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological situations, suggesting methods to developing Vitality-transducing motors at nanoscale interfaces.
There was just one trouble though — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule level, conducting polymers were really not this sort of wonderful conductors, which was somewhat disappointing. We So broadened our perspective to test to uncover extra promising molecules.
‘The idea that There's this type of matter to be a beginning, a huge bang, is now a fascinating signpost to think about that there was a creator. But a lot more commonly, and on The premise of pure rationality, I also get there in a Christian interpretation of truth. An atheistic worldview is really a naturalistic worldview: fundamentally, you'll find only atoms and normal forces that we could evaluate.
Cees Dekker is Distinguished University Professor at TU Delft. Skilled like a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes while in the nineties. Considering that 2000, he moved to solitary-molecule biophysics and nanobiology. His recent analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is really an elected member of your KNAW and fellow to your APS plus the IOP.
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It absolutely was an extremely attention-grabbing time, throughout which I gained a lot of help from Delft College of Technological know-how, exactly where I used to be a professor at enough time, And that i started numerous collaborations with molecular biologists. That aided me study a lot.’